Search results for " lymphoscintigraphy"

showing 5 items of 5 documents

Comparison of 99mTc-Labeled Colloid SPECT/CT and Planar Lymphoscintigraphy in Sentinel Lymph Node Detection in Patients with Melanoma: A Meta-Analysis

2020

We compared the detection rate (DR) for sentinel lymph nodes (SLNS), the number of SLNs and the subjects with additional SLNs of single-photon emission computed tomography (SPECT/CT) and planar lymphoscintigraphy (PL) in patients with melanoma. Furthermore, we evaluated the impact of SPECT/CT on surgical plans. Articles containing head-to-head comparisons between SPECT/CT and PL were searched in Pubmed/MEDLINE and Scopus. The literature search was updated until December 31st, 2019. DR was calculated on a per-patient-based analysis; the studies were pooled by their odds ratios (ORs) with a random effects model to assess the significance of difference (p < 0.05). The number of additional S…

planar lymphoscintigraphySentinel lymph nodelcsh:MedicineSingle-photon emission computed tomography030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinesentinel lymph node99mTc-labeled colloidsmedicinemelanomamedicine.diagnostic_testbusiness.industryMelanomalcsh:RGeneral MedicineOdds ratiomedicine.diseaseConfidence intervalbody regionsmeta-analysis<sup>99m</sup>Tc-labeled colloids030220 oncology & carcinogenesisRelative riskMeta-analysis99mTc-labeled colloids; melanoma; meta-analysis; planar lymphoscintigraphy; sentinel lymph node; single photon emission/computed tomographysingle photon emission/computed tomographyNuclear medicinebusinessEmission computed tomographyJournal of Clinical Medicine
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Lymphoscintigraphy for the diagnosis of extremity lymphedema: Current controversies regarding protocol, interpretation, and clinical application

2019

Appropriate diagnosis, staging and a further selection of the best treatment are fundamental for the management of patients with extremity lymphedema. Several clinical and imaging tools have been described for these purposes. Lymphoscintigraphy is still considered the gold standard imaging modality for diagnosing lymphedema. However, protocol variability and poor image resolution can make the interpretation challenging. Here, we reviewed technical aspects of lymphoscintigraphy, interpretation of the lymphoscintigraphy findings, staging, and its clinical application.

Protocol (science)medicine.medical_specialtybusiness.industryGeneral MedicineGold standard (test)medicine.disease03 medical and health sciencesextremity lymphedema; lymphatic microsurgery; lymphedema diagnosis; Lymphedema Grading System; lymphoscintigraphy; Humans; Lymphedema; Lymphoscintigraphy0302 clinical medicineLymphedemaOncology030220 oncology & carcinogenesismedicineHumans030211 gastroenterology & hepatologySurgeryLymphedemaRadiologybusinessLymphoscintigraphyJournal of Surgical Oncology
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Sentinel Node Identification in Melanoma: Current Clinical Impact, New Emerging SPECT Radiotracers and Technological Advancements. An Update of the L…

2020

Background: Melanoma is the most lethal skin cancer with a mortality rate of 262 cases per 100.000 cases. The sentinel lymph node (SLN) is the first lymph node draining the tumor. SLN biopsy is a widely accepted procedure in the clinical setting since it provides important prognostic information, which helps patient management, and avoids the side effects of complete lymph node dissection. The rationale of identifying and removing the SLN relies on the low probability of subsequent metastatic nodes in case of a negative histological exam performed in the SLN. Discussion: Recently, new analytical approaches, based on the evaluation of scintigraphic images are also exploring the possibility …

medicine.medical_specialtySingle Photon Emission Computed Tomography Computed TomographySkin NeoplasmsSentinel lymph nodeSingle-photon emission computed tomographySentinel lymph node biopsyhybrid imagingBiopsymedicineHumansRadiology Nuclear Medicine and imagingsentinel lymph node biopsyMelanomaLymph nodePharmacology99mTc-Tilmanoceptmedicine.diagnostic_testbusiness.industryMelanomaSPECT/CTSentinel nodePrognosismedicine.disease99mTc-colloids; 99mTc-Tilmanocept; Hybrid imaging; Melanoma; Sentinel lymph node biopsy; SPECT/CT; Humans; Lymphoscintigraphy; Melanoma; Prognosis; Radiopharmaceuticals; Sentinel Lymph Node; Single Photon Emission Computed Tomography Computed Tomography; Skin NeoplasmsDissectionHybrid imagingmedicine.anatomical_structure99mTc-colloidsRadiologyRadiopharmaceuticalsSentinel Lymph NodeSkin cancerbusinessLymphoscintigraphyCurrent Radiopharmaceuticals
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Lymphoscintigraphy with peritumoral injection versus lymphoscintigraphy with subdermal periareolar injection of technetium-labeled human albumin to i…

2014

Background Preoperative lymphoscintigraphy is without doubt a valid method for the detection of the sentinel lymph node (SLN). There has been considerable debate regarding the optimal site for the introduction of the tracer; various sites include peritumoral (PT), periareolar (PA), subdermal, and intradermal injection. Purpose To evaluate retrospectively the lymphoscintigraphic identification rate of peritumoral (PT) injection versus subdermal periareolar (PA) injection in the detection of SLNs in breast cancer. Material and Methods Between October 2002 and December 2011, a cohort of 906 consecutive patients with biopsy proven breast cancer underwent 914 SLN biopsy procedures. A total of 33…

Adultmedicine.medical_specialtySentinel lymph nodechemistry.chemical_elementBreast NeoplasmsInjections IntralesionalTechnetiumPeriareolarBreast cancerBiopsymedicineCarcinomaHumansRadiology Nuclear Medicine and imagingTechnetium Tc 99m Aggregated AlbuminAgedRetrospective StudiesAged 80 and overBreast cancer sentinel lymph node biopsy lymphoscintigraphy sub areolar peritumoral radio-colloidRadiological and Ultrasound Technologymedicine.diagnostic_testSentinel Lymph Node Biopsybusiness.industryHuman albuminGeneral MedicineMiddle AgedImage Enhancementmedicine.diseaseSurgerychemistryFemaleLymphRadiopharmaceuticalsSettore MED/36 - Diagnostica Per Immagini E RadioterapiaNuclear medicinebusinessLymphoscintigraphyActa Radiologica
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Validity of the Novel Taiwan Lymphoscintigraphy Staging and Correlation of Cheng Lymphedema Grading for Unilateral Extremity Lymphedema

2018

Objective: The aim was to validate the new Taiwan Lymphoscintigraphy Staging, correlate it with Cheng Lymphedema Grading (CLG) and evaluate the treatment outcomes of unilateral extremity lymphedema. Background: No consensus has been reached for diagnosis and staging for patients with lymphedema among medical specialties. Methods: We included 285 patients with unilateral extremity lymphedema using lymphoscintigraphy. Lymphoscintigraphy was correlated to clinical symptoms and signs, and classified into normal lymphatic drainage, partial obstruction, and total obstruction. Inter- and intraobserver reliability of Taiwan Lymphoscintigraphy Staging, correlation between Taiwan Lymphoscintigraphy S…

Malemedicine.medical_specialtyValidation studyextremity lymphedemaTreatment outcomeTaiwanMEDLINEbreast cancer-related lymphedema030230 surgery03 medical and health scienceslymphoscintigraphy0302 clinical medicinehemic and lymphatic diseasesmedicineHumansLymphedemaGrading (tumors)breast cancer-related lymphedema; extremity lymphedema; lymphatic microsurgery; lymphedema diagnosis; Cheng Lymphedema Grading System; lymphoscintigraphy; Extremities; Female; Humans; Lymphedema; Lymphoscintigraphy; Male; Middle Aged; Reproducibility of Results; TaiwanExtramuralbusiness.industryReproducibility of ResultsExtremitiesMiddle Agedmedicine.diseaselymphatic microsurgeryhumanitiesbody regionsLymphedema030220 oncology & carcinogenesisCheng Lymphedema Grading SystemFemaleSurgeryRadiologylymphedema diagnosibusinessBreast Cancer Related Lymphedema
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